Chroneme reads how your health changes over time. Every signal, from every provider, across years. And when something is developing, it knows. Before the doctor. Before the diagnosis. Before the emergency. No black box, by design. Intelligence clinicians can question, understand, and trust.
We tested Chroneme across hundreds of thousands of ICU stays from 208 hospitals. It detected deterioration hours to days before standard scoring systems flagged anything. AUROC 0.926, outperforming the best general-purpose AI (0.849) on the same clinical data.
Zohaib Akhtar is the founder of Chroneme. His cross-disciplinary background spans medicine, public health, biomedical design, business, and AI systems. Also founder of OpenCura. 13 patent families filed.
Chenyu Li, Co-Founder. Adam Wolfe, Co-Founder.
Founded 2025. Chroneme, Inc. 13 patent families filed. Contact: mail@chroneme.com
Chroneme has been validated across hundreds of thousands of ICU stays from 208 hospitals using the eICU Collaborative Research Database and MIMIC-IV. It detected clinical deterioration hours to days before standard ICU early warning systems flagged anything.
AUROC 0.926 for Chroneme versus 0.849 for the best general-purpose AI (Claude Sonnet 4.6). Same data, same conditions. Deterministic clinical decision support outperforming black-box AI.
Lead time: median 35 hours before standard scoring systems. Validated across multiple patient populations, age groups, and ICU types.